Research

Faculty in the Computational Biology program are engaged in cutting-edge research in a variety of areas, including computational genomics, systems biology, and bioinformatics. The best way to learn about the research being done by our faculty is to visit their websites and read their recent publications. You can find a list of faculty members and their websites on the faculty page. Here are some recent publications by our faculty:

Recent publications

PEPhub: a database, web interface, and API for editing, sharing, and validating biological sample metadata.

Toxoplasma gondii infection supports the infiltration of T cells into brain tumors.

Protocol for iterative indirect immunofluorescence imaging in cultured cells, tissue sections, and metaphase chromosome spreads.

Antihypertensive Drugs for the Prevention of Atrial Fibrillation: A Drug Target Mendelian Randomization Study.

Multicellular immune ecotypes within solid tumors predict real-world therapeutic benefits with immune checkpoint inhibitors.

CoDIAC: A comprehensive approach for interaction analysis reveals novel insights into SH2 domain function and regulation.

Characterizing microglial signaling dynamics during inflammation using single-cell mass cytometry.

Methods for evaluating unsupervised vector representations of genomic regions.

Tobacco smoking is associated with sex- and plaque-type specific upregulation of CRLF1 in atherosclerotic lesions.

Modeling the roles of cohesotaxis, cell-intercalation, and tissue geometry in collective cell migration of Xenopus mesendoderm.

Multi-omic analysis reveals VEGFR2, PI3K, and JNK mediate the small molecule induction of human iPSC-derived cardiomyocyte proliferation.

Methods for constructing and evaluating consensus genomic interval sets.

Hyperlipidemia-induced hematopoiesis is repressed by MLKL in endothelial cells of the splenic niche.

Brain Microvascular Pericyte Pathology Linking Alzheimer's Disease to Diabetes.

An aberrant immune-epithelial progenitor niche drives viral lung sequelae.